Grupo de productos: Productos Life Science

Is it possible to use BRANDplates® inserts with Inlet Opening System (IOS) for experiments with monolayer formation?

It depends on the experimental design. Cell maturation is usually induced by serum deprivation in the apical compartment while cells still get nutrient supply from the lower compartment. Apical-basolateral medium  intermixing by the IOS in principle exists. Therefore, BRANDplates® without IOS are recommended.